Originally created in 2004, Prometheus is a project of University of Colorado's Center for Science and Technology Policy Research. Prometheus is designed to create an informal outlet for news, information, and opinion on science and technology policy.
Ash tree killed by the invasive emerald ash borer. Photo: K Steve Cope.
by Jason Delborne CSTPR Faculty Affiliate and Associate Professor of Science, Policy, and Society in the Department of Forestry and Environmental Resources, North Carolina State University
But releasing genetically engineered trees into forests to counter threats to forest health represents a new frontier in biotechnology. Even as the techniques of molecular biology have advanced, humans have not yet released a genetically engineered plant that is intended to spread and persist in an unmanaged environment. Biotech trees – genetically engineered or gene-edited – offer just that possibility.
One thing is clear: The threats facing our forests are many, and the health of these ecosystems is getting worse. A 2012 assessment by the U.S. Forest Service estimated that nearly 7 percent of forests nationwide are in danger of losing at least a quarter of their tree vegetation by 2027. This estimate may not sound too worrisome, but it is 40 percent higher than the previous estimate made just six years earlier.
Our committee members came from universities, federal agencies and NGOs and represented a range of disciplines: molecular biology, economics, forest ecology, law, tree breeding, ethics, population genetics and sociology. All of these perspectives were important for considering the many aspects and challenges of using biotechnology to improve forest health.
More than 80 million acres are at risk of losing at least 25 percent of tree vegetation between 2013 and 2027 due to insects and diseases. Credit: Krist et al. (2014), CC BY-SA.
A crisis in US forests Climate change is just the tip of the iceberg. Forests face higher temperatures and droughts and more pests. As goods and people move around the globe, even more insects and pathogens hitchhike into our forests.
We focused on four case studies to illustrate the breadth of forest threats. The emerald ash borer arrived from Asia and causes severe mortality in five species of ash trees. First detected on U.S. soil in 2002, it had spread to 31 states as of May 2018. Whitebark pine, a keystone and foundational species in high elevations of the U.S. and Canada, is under attack by the native mountain pine beetle and an introduced fungus. Over half of whitebark pine in the northern U.S. and Canada have died.
The emerald ash borer is destroying ash trees in 31 states. Photo: Herman Wong HM/Shutterstock.The emerald ash borer feeds on ash trees, damaging and eventually killing them. Photo: K Steve Cope/Shutterstock.
Poplar trees are important to riparian ecosystems as well as for the forest products industry. A native fungal pathogen, Septoria musiva, has begun moving west, attacking natural populations of black cottonwood in Pacific Northwest forests and intensively cultivated hybrid poplar in Ontario. And the infamous chestnut blight, a fungus accidentally introduced from Asia to North America in the late 1800s, wiped out billions of American chestnut trees.
Can biotech come to the rescue? Should it?
It’s complicated Although there are many potential applications of biotechnology in forests, such as genetically engineering insect pests to suppress their populations, we focused specifically on biotech trees that could resist pests and pathogens. Through genetic engineering, for example, researchers could insert genes, from a similar or unrelated species, that help a tree tolerate or fight an insect or fungus.
It’s tempting to assume that the buzz and enthusiasm for gene editing will guarantee quick, easy and cheap solutions to these problems. But making a biotech tree will not be easy. Trees are large and long-lived, which means that research to test the durability and stability of an introduced trait will be expensive and take decades or longer. We also don’t know nearly as much about the complex and enormous genomes of trees, compared to lab favorites such as fruit flies and the mustard plant, Arabidopsis.
In addition, because trees need to survive over time and adapt to changing environments, it is essential to preserve and incorporate their existing genetic diversity into any “new” tree. Through evolutionary processes, tree populations already have many important adaptations to varied threats, and losing those could be disastrous. So even the fanciest biotech tree will ultimately depend on a thoughtful and deliberate breeding program to ensure long-term survival. For these reasons, the National Academies of Sciences, Engineering, and Medicine committee recommends increasing investment not just in biotechnology research, but also in tree breeding, forest ecology and population genetics. Read more …
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Can Genetic Engineering Save Disappearing Forests
by Jason Delborne
CSTPR Faculty Affiliate and Associate Professor of Science, Policy, and Society in the Department of Forestry and Environmental Resources, North Carolina State University
Originally published in The Conversation
Compared to gene-edited babies in China and ambitious projects to rescue woolly mammoths from extinction, biotech trees might sound pretty tame.
But releasing genetically engineered trees into forests to counter threats to forest health represents a new frontier in biotechnology. Even as the techniques of molecular biology have advanced, humans have not yet released a genetically engineered plant that is intended to spread and persist in an unmanaged environment. Biotech trees – genetically engineered or gene-edited – offer just that possibility.
One thing is clear: The threats facing our forests are many, and the health of these ecosystems is getting worse. A 2012 assessment by the U.S. Forest Service estimated that nearly 7 percent of forests nationwide are in danger of losing at least a quarter of their tree vegetation by 2027. This estimate may not sound too worrisome, but it is 40 percent higher than the previous estimate made just six years earlier.
In 2018, at the request of several U.S. federal agencies and the U.S. Endowment for Forestry and Communities, the National Academies of Sciences, Engineering, and Medicine formed a committee to “examine the potential use of biotechnology to mitigate threats to forest tree health.” Experts, including me, a social scientist focused on emerging biotechnologies, were asked to “identify the ecological, ethical, and social implications of deploying biotechnology in forests, and develop a research agenda to address knowledge gaps.”
Our committee members came from universities, federal agencies and NGOs and represented a range of disciplines: molecular biology, economics, forest ecology, law, tree breeding, ethics, population genetics and sociology. All of these perspectives were important for considering the many aspects and challenges of using biotechnology to improve forest health.
A crisis in US forests
Climate change is just the tip of the iceberg. Forests face higher temperatures and droughts and more pests. As goods and people move around the globe, even more insects and pathogens hitchhike into our forests.
We focused on four case studies to illustrate the breadth of forest threats. The emerald ash borer arrived from Asia and causes severe mortality in five species of ash trees. First detected on U.S. soil in 2002, it had spread to 31 states as of May 2018. Whitebark pine, a keystone and foundational species in high elevations of the U.S. and Canada, is under attack by the native mountain pine beetle and an introduced fungus. Over half of whitebark pine in the northern U.S. and Canada have died.
Poplar trees are important to riparian ecosystems as well as for the forest products industry. A native fungal pathogen, Septoria musiva, has begun moving west, attacking natural populations of black cottonwood in Pacific Northwest forests and intensively cultivated hybrid poplar in Ontario. And the infamous chestnut blight, a fungus accidentally introduced from Asia to North America in the late 1800s, wiped out billions of American chestnut trees.
Can biotech come to the rescue? Should it?
It’s complicated
Although there are many potential applications of biotechnology in forests, such as genetically engineering insect pests to suppress their populations, we focused specifically on biotech trees that could resist pests and pathogens. Through genetic engineering, for example, researchers could insert genes, from a similar or unrelated species, that help a tree tolerate or fight an insect or fungus.
It’s tempting to assume that the buzz and enthusiasm for gene editing will guarantee quick, easy and cheap solutions to these problems. But making a biotech tree will not be easy. Trees are large and long-lived, which means that research to test the durability and stability of an introduced trait will be expensive and take decades or longer. We also don’t know nearly as much about the complex and enormous genomes of trees, compared to lab favorites such as fruit flies and the mustard plant, Arabidopsis.
In addition, because trees need to survive over time and adapt to changing environments, it is essential to preserve and incorporate their existing genetic diversity into any “new” tree. Through evolutionary processes, tree populations already have many important adaptations to varied threats, and losing those could be disastrous. So even the fanciest biotech tree will ultimately depend on a thoughtful and deliberate breeding program to ensure long-term survival. For these reasons, the National Academies of Sciences, Engineering, and Medicine committee recommends increasing investment not just in biotechnology research, but also in tree breeding, forest ecology and population genetics. Read more …